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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STXBP5 All Species: 29.7
Human Site: S418 Identified Species: 72.59
UniProt: Q5T5C0 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T5C0 NP_001121187.1 1151 127573 S418 D L I P A L Y S V G A R Q K R
Chimpanzee Pan troglodytes XP_516678 1303 144261 S548 D L I L V L Y S I G V K H K K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533442 1260 139162 S527 D L I P A L Y S V G A R Q K R
Cat Felis silvestris
Mouse Mus musculus Q8K400 1152 127638 S419 D L I P A L Y S V G A R Q K R
Rat Rattus norvegicus Q9WU70 1152 127641 S419 D L I P A L Y S V G A R Q K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507080 1121 123964 S424 E L I P A L Y S V G V R Q K R
Chicken Gallus gallus XP_419658 1115 123181 S419 D L I P A L Y S V G A R Q K R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5SQE2 1159 128185 S432 D I I P V L Y S I G A K H K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08111 1161 126874 R398 S V Y E S I L R A G D E Q D I
Honey Bee Apis mellifera XP_391820 1090 120734 V401 A D C P S D L V P A F Y S V G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.2 N.A. 89.9 N.A. 96.8 96.8 N.A. 92 90.3 N.A. 63.8 N.A. 22.1 50.5 N.A. N.A.
Protein Similarity: 100 72.8 N.A. 90.5 N.A. 98.3 98.2 N.A. 94.8 93.3 N.A. 79.2 N.A. 40.7 68.4 N.A. N.A.
P-Site Identity: 100 53.3 N.A. 100 N.A. 100 100 N.A. 86.6 100 N.A. 60 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 73.3 N.A. 100 N.A. 100 100 N.A. 93.3 100 N.A. 86.6 N.A. 33.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 60 0 0 0 10 10 60 0 0 0 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 70 10 0 0 0 10 0 0 0 0 10 0 0 10 0 % D
% Glu: 10 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 90 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % H
% Ile: 0 10 80 0 0 10 0 0 20 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 20 0 80 20 % K
% Leu: 0 70 0 10 0 80 20 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 80 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 70 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 60 0 0 60 % R
% Ser: 10 0 0 0 20 0 0 80 0 0 0 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 20 0 0 10 60 0 20 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 80 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _